KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
23.64
Human Site:
S238
Identified Species:
47.27
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
S238
L
R
P
K
D
L
W
S
L
G
R
E
N
S
S
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
I107
M
R
I
K
T
A
V
I
G
A
V
Y
R
K
A
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
G207
S
N
A
C
P
E
A
G
A
S
F
P
S
K
A
Dog
Lupus familis
XP_547113
1504
165780
S238
L
G
P
E
D
L
W
S
L
G
R
E
N
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
S244
L
G
P
K
D
L
W
S
L
G
R
E
N
S
S
Rat
Rattus norvegicus
O88269
1502
164977
S244
L
G
P
K
D
L
W
S
L
E
R
E
N
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
S255
L
E
A
S
D
L
W
S
L
N
R
E
D
T
S
Chicken
Gallus gallus
Q5F364
1525
170953
S243
L
E
A
K
D
L
W
S
L
N
K
E
D
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
S243
L
E
E
K
D
L
W
S
L
N
N
E
D
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
H150
P
T
T
F
G
I
H
H
V
C
F
K
M
R
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
V239
A
P
A
K
S
N
D
V
V
V
E
K
S
E
N
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
Y237
M
K
T
G
Y
E
K
Y
L
V
E
A
D
L
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
86.6
N.A.
93.3
86.6
N.A.
60
60
N.A.
60
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
13.3
93.3
N.A.
93.3
86.6
N.A.
73.3
80
N.A.
66.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
34
0
0
9
9
0
9
9
0
9
0
0
17
% A
% Cys:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
59
0
9
0
0
0
0
0
34
0
0
% D
% Glu:
0
25
9
9
0
17
0
0
0
9
17
59
0
9
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
25
0
9
9
0
0
9
9
25
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
59
0
0
9
0
0
0
9
17
0
25
0
% K
% Leu:
59
0
0
0
0
59
0
0
67
0
0
0
0
9
0
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
25
9
0
34
0
9
% N
% Pro:
9
9
34
0
9
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
0
0
0
0
0
0
0
0
42
0
9
9
0
% R
% Ser:
9
0
0
9
9
0
0
59
0
9
0
0
17
34
59
% S
% Thr:
0
9
17
0
9
0
0
0
0
0
0
0
0
17
0
% T
% Val:
0
0
0
0
0
0
9
9
17
17
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
59
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
9
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _